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Abstract
Sorge and his adviser at McGill University, pain researcher Jeffrey Mogil, would go on to determine that this kind of pain hypersensitivity results from remarkably different pathways in male and female mice, with distinct immune-cell types contributing to discomfort2. [...]if the roots ofpain are different, some drugs might work better in some people than in others. [...]people might require different pain medications when hormone levels fluctuate through life. Testosterone, the hormone involved in development of the penis, testes and prostate, as well as of secondary characteristics such as body hair, has received much less attention from pain researchers, although studies suggest it can reduce pain3, and some people with chronic pain take testosterone treatments4. [...]drugs are mostly trialled on men and on women who are past menopause.