Content area

Abstract

Paper is predominantly composed of cellulose fibers that have an inherent ability to wick fluids by capillary action; it provides an interesting diagnostic platform that is inexpensive, easily obtained, and eco-friendly. Paper has been used in various types of biologically relevant applications including paper-based molecular assays, paper-based ELISA (P-ELISA), paper-based nucleic acid assays, and paper-based cell assays. Based on recent successes with the use of paper as a platform, we contend that paper is not only very suitable for diagnostics but could provide a more advantageous platform than current plastics-based platforms for drug discovery, and would be useful for accomplishingin vitropre-compound screening steps while offering a possible solution to several economic obstacles inherent in the pharmaceutical industry.

Details

Title
Paper - a potential platform in pharmaceutical development
Author
Chen, Yi-Hsun; Kuo, Zong-Keng; Cheng, Chao-Min
Pages
4-9
Publication year
2015
Publication date
Jan 2015
Publisher
Elsevier Limited
ISSN
01677799
e-ISSN
18793096
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
1638174678
Copyright
Copyright Elsevier Limited Jan 2015