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A 20-month-old boy, who had scabies, developed metabolic acidosis, nausea, vomiting, dyspnoea, tachypnoea and sinus tachycardia after extensive dermal exposure; in addition, he may have put his permethrin-contaminated hands in his mouth.
The boy's parents had applied 5% permethrin lotion 60mL over three consecutive days (approximately 20 mL/day); the drug was applied to his entire body except his face and head for the treatment of scabies. He was...