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Abstract
To the Editor: In their article on Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL) in children, adolescents, and young adults, Roberts and colleagues (Sept. 11 issue)1 note that the frequency of Ph-like ALL in older adults is currently unknown. We analyzed Affymetrix gene-expression profiles of 204 B-cell precursor ALL specimens obtained from 92 adolescents and young adults (16 to 39 years of age), 45 adults (40 to 55 years of age), and 67 older adults (56 to 84 years of age) who received treatment in German Multicenter Study . . .
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1 Klinikum der Universität München, Munich, Germany
2 Charité–Universitätsmedizin Berlin, Berlin, Germany
3 University Hospital, Frankfurt, Germany