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Exp Brain Res (2015) 233:13391349 DOI 10.1007/s00221-015-4206-z
RESEARCH ARTICLE
Poor motor function is associated with reduced sensory processing after stroke
S. Floor Campfens Sarah B. Zandvliet
Carel G. M. Meskers Alfred C. Schouten Michel J. A. M. van Putten Herman van der Kooij
Abstract The possibility to regain motor function after stroke depends on the intactness of motor and sensory pathways. In this study, we evaluated afferent sensory pathway information transfer and processing after stroke with the coherence between cortical activity and a position perturbation (position-cortical coherence, PCC). Eleven subacute stroke survivors participated in this study. Subjects performed a motor task with the affected and non-affected arm while continuous wrist position perturbations were applied. Cortical activity was measured using EEG. PCC was calculated between position perturbation and EEG at the contralateral and ipsilateral sensorimotor area. The presence of PCC was quantied as the number of frequencies where PCC is larger than zero across the sensorimotor area. All subjects showed signicant contralateral PCC in affected and non-affected wrist tasks. Subjects with poor motor function had a reduced presence of contralateral PCC compared with subjects with good motor function in the affected wrist tasks. Amplitude of signicant PCC did not
S. F. Campfens (*) A. C. Schouten H. van der Kooij Department of Biomechanical Engineering, MIRA Instituteof Biomedical Engineering and Technical Medicine, University of Twente, PO Box 217, 7500 AE Enschede, The Netherlands e-mail: [email protected]
S. F. Campfens M. J. A. M. van Putten
Clinical Neurophysiology, MIRA Institute of Biomedical Engineering and Technical Medicine, University of Twente, Enschede, The Netherlands
S. B. Zandvliet C. G. M. Meskers
Department of Rehabilitation Medicine, Leiden University Medical Center, Leiden, The Netherlands
A. C. Schouten H. van der Kooij
Department of Biomechanical Engineering, Delft University of Technology, Delft, The Netherlands
Received: 9 May 2014 / Accepted: 13 January 2015 / Published online: 5 February 2015 The Author(s) 2015. This article is published with open access at Springerlink.com
differ between subjects with good and poor motor function.
Our results show that poor motor function is associated with reduced sensory pathway information transfer and processing in subacute stroke subjects. Position-cortical coherence may provide additional insight into mechanisms of recovery of motor function after stroke.
Keywords Stroke Coherence Afferent pathways
Motor control Joint position...