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Copyright © 2014 Nazmiye Selçuk Kapısız et al. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

The objective of the study is to evaluate a range of potential risk factors in the etiology of varicose veins with superficial venous reflux. Forty-nine patients attending a cardiovascular surgery clinic for the management of varicose disease between 2009 and 2010 were enrolled for the study. The age range of the patient group was 44,04 ± 15,05 years and female/male (F/M) ratio was 30/19. Twenty-six normal, healthy volunteers with the age of 40,94 ± 13,60 years and with the female/male ratio of 15/11 acted as control subjects. We investigated several parameters including body mass index, age, birth number > 1, standing for a long time (standing for 8 or more hours without taking a break), systemic diseases, family history, venous Doppler fındings, the levels of homocysteine, ferritin, vitamin B12, and hemoglobin, sedimentation rate, mean corpuscular volume, low density lipoprotein, and rheumatoid factor of the patient group and the control group. We also determined the contribution of the methylene tetrahydrofolate reductase 677 C>T and 1298 A>C gene polymorphisms and FV Leiden in both groups. In this small study, there appears to be no association between varicose veins and body mass index, smoking, type 2 DM, hypertension, family history, and birth number. A history of increased standing duration period (>8 hours) and rheumatoid factor positivity have association with varicose veins with superficial venous reflux.

Details

Title
Potential Risk Factors for Varicose Veins with Superficial Venous Reflux
Author
Kapısız, Nazmiye Selçuk 1   VIAFID ORCID Logo  ; Tülin Uzun Kulaoğlu 2 ; Turgay Fen 3 ; Hasan Fahri Kapısız 4 

 Cardiovascular Surgery Department, Atatürk Education and Research Hospital, Bilkent, 06800 Ankara, Turkey 
 Radiology Department, Ankara Education and Research Hospital, 06340 Ankara, Turkey 
 Hematology Department, Ankara Education and Research Hospital, 06340 Ankara, Turkey 
 Cardiovascular Surgery Department, Ankara Yenimahalle State Hospital, 06170 Ankara, Turkey 
Editor
Bhagwan Satiani
Publication year
2014
Publication date
2014
Publisher
John Wiley & Sons, Inc.
ISSN
20902824
e-ISSN
20902832
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2407633154
Copyright
Copyright © 2014 Nazmiye Selçuk Kapısız et al. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.