Content area

Abstract

This review discusses methods for the single-chain antibody fragment (scFv) generation and scFv expression systems, and describes potential applications of scFv in the therapy of viral diseases and cancer, with emphasis on intracellularly expressed scFvs (intrabodies), application of scFvs in detection and diagnostics, and their use in proteomics.

Details

Title
The production and application of single-chain antibody fragments
Author
Blažek, D. 1 ; Celer, V. 1 

1  Veterinary and Pharmaceutical University, Institute of Microbiology and Immunology, Faculty of Veterinary Medicine, Brno, Czechia 
Pages
687-698
Publication year
2003
Publication date
Sep 2003
Publisher
Springer Nature B.V.
ISSN
00155632
e-ISSN
18749356
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1007/BF02993480
ProQuest document ID
754948313
Copyright
© Institute of Microbiology, Academy of Sciences of the Czech Republic 2003.