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EDITOR-Jefferson's editorial about vaccination and its adverse effects mentions our research. 1 We found that immunisation starting at birth was associated with a decreased risk of insulin dependent diabetes, while immunisation starting after age 2months was associated with an increased risk of diabetes in both rodents and humans. 2 We initiated a collaboration with Dr Jaakko Tuomilehto to study the effect of Haemophilus influenzae type b vaccine on the incidence of diabetes. Roughly116000 Finnish children were randomised to receive either four doses of the vaccine, starting at 3months of age, or one dose at 24months of age. 3 We calculated the incidence of insulin dependent diabetes in both groups until age 10and in a group that did not receive the vaccine-a cohort that included all 128500 children born in Finland in the 24months before the study of the vaccine began.
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