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ABSTRACT
Hair loss is a frequently seen side-effect of psychotropic medicaments. Beside the psychotropic medicaments valproic acid and lithium, mostly blamed for alopecia, also cases due to use of antidepressants and typical/atypical antipsychotics have been reported. However, studies on alopecia caused by atypical antipsychotic drugs are scarce and limited by case reports. In this paper, a 16-year-old adolescent female patient developing diffuse alopecia associated with use of quetiapine and recovering after cessation of the medicament is presented. As far as we know, this is the first case reporting quetiapine-associated alopecia in an adolescent. (Anatolian Journal of Psychiatry 2015; 16(2):143-145)
Key words: quetiapine, alopecia, side effects, adolescent
Bir ergen olguda ketiyapin kullanimina bagli saç dökülmesi
ÖZET
Saç dökülmesi psikotrop ilaçlarin sik görülen bir yan etkisidir. Ancak atipik antipsikotiklere bagli saç dökülmesi ile ilgili yayin sayisi oldukça azdir ve olgu sunumlariyla sinirlidir. Bu yazida, ketiyapin baslanmasi sonucu ortaya çikan ve tedavinin sonlandirilmasiyla düzelen, yaygin saç dökülmesi olan 16 yasinda ergen kiz olgu bildirilmistir. Bildigimiz kadariyla olgumuz, ergenlik yas grubunda ketiyapinle iliskili saç dökülmesi oldugu bildirilen ilk olgudur. (Anadolu Psikiyatri Derg 2015; 16(2):143-145)
Anahtar sözcükler: Ketiyapin, alopesi, yan etkiler, ergen
INTRODUCTION
The term alopecia describes the spectrum of loss of hair in every phase ranging from a simple defluxium to a total hair loss. Alopecia is seen most frequently in scalp hair. Alopecia is quite frequently encountered in daily medical practice. Among causes of alopecia, genetic factors are in the first line; the other causes are pregnancy, thyroid disorders, iron-deficiency anemia, infectious diseases, drugs, malnutrition and psychological stress. Alopecia is not a life-threatening disorder, but may have a negative effect on social life.1
Drug-induced alopecia is a quite frequently seen side-effect. It has been reported that many medicaments may cause alopecia by changing the normal cycles of hair follicle growth, that is, from the long growing phase suddenly to resting phase.2 Diffuse alopecia can be caused by antineoplastic chemotherapy, antithyroid medicaments, oral contraceptives, anticoagulants, antiepileptics, beta-blockers, nonsteroid antiinflammatory drugs and psychotropic drugs.2 Druginduced alopecia is generally diffuse, leaves no scar and reversible with cessation of the responsible drug.2
Alopecia caused by psychotropic medicaments is a frequently seen disorder.3 Beside the psychotropic medicaments valproic acid and lithium, the mostly blamed for alopecia,4-8 also cases due to use...