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Amac: Rekürren aftöz stomatit (RAS) ve Behcet hastaliginda (BH'de) görülen oral ülserlerin ve diger klinik özelliklerin karSilaStirilmasi

Gerec ve Yöntem: CaliSmaya RAS tanisi ile izlenen, 20-54 yaS araliginda, 20'si kadin, 10'u erkek toplam 30 RAS hastasi; BH tanisi ile izlenen, 19-47 yaS araliginda, 32'si kadin, 17'si erkek toplam 49 Behcet hastasi alindi. RAS tanisi; yilda üc kereden fazla oral ülser yakinmasi olan, aft veya aft benzeri lezyonlara yol acan diger klinik durumlardan ayrimi yapilmiS hastalari kapsadi. BH tanisi Uluslararasi CaliSma Grubu Tani Kriterlerine göre konuldu. Her iki hasta grubu aile hikayesi, hastalik baSlangi c yaSi, hastalik süresi, oral aft sikligi ve süresi yönünden sorgulandi; dermatolojik muayenede görülen oral aft boyutu, lokalizasyonu, sayisi kaydedildi. Istatistiksel degerlendirmelerde Student's t testi ve Mann Whitney U testi kullanildi.

Bulgular: Behcet hastalarinin hastalik baSlangic yaSinin RAS hastalarina kiyasla daha genc oldugu saptandi ve bu fark istatistiksel olarak anlamli bulundu.

Sonuc: Tekrarlayan oral ülser Sikayeti genc yaSta baSlayan ve cok sayida oral ülseri olan hastalarda öncelikli olarak BH, labial mukoza yerleSimli ülseri olan hastalarda ise öncelikli olarak RAS öntanisi akla gelmesi gerektigi düSünülse de bu konuda daha geniS hasta serilerinde caliSmalar yapilmasina ihtiyac vardir. (Türkderm 2010; 44: 150-2)

Anahtar Kelimeler: Rekürren aftöz stomatit, Behcet hastaligi

Summary

Background and Design: To compare the oral ulcerations and other clinical features seen in recurrent aphthous stomatitis (RAS) and Behçet's disease (BD).

Material and Method: Thirty RAS patients (20 female, 10 male), aged 20-54 years and 49 Behçet patients (32 female, 17 male), aged 19-47 years, were included in the study. Diagnosis of RAS was made in the patients who have oral ulcerations more than 3 times per year, and who does not suffer from diseases, which may cause aphthous or aphthous-like lesions. The diagnosis of BD was established according to the criteria of the International Study Group for BD. Both groups were examined for family history, age at onset, disease duration, frequency and duration of oral aphtae; additionally, during dermatological examination, dimension, localization and number of oral aphthae were recorded. Student's t-test and Mann-Whitney U tests were used for statistical analysis.

Results: The mean age at onset of the disease was lower in Behçet patients than in RAS patients, and this difference was statistically significant.

Conclusion: Although BD is usually considered...

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