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Bulletin of Experimental Biology and Medicine, Vol. 150, No. 1, December, 2010
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SPORTS MEDICINE Relationship between Lactate Concentrations
in Active Muscle Sweat and Whole Blood
D. A. Sakharov, M. U. Shkurnikov, M. Yu. Vagin*, E. I. Yashina*, A. A. Karyakin*, and A. G. Tonevitsky
Translated from Byulleten Eksperimentalnoi Biologii i Meditsiny, Vol. 150, No. 7, pp. 94-96, July, 2010 Original article submitted November 18, 2009
Lactate (lactic acid) concentrations in sweat and venous and capillary blood of athletes were measured before and after exercise of the maximum aerobic power. Correlations between the increment of blood and sweat lactate concentrations were found. Lactate concentrations in the sweat can be used for evaluation of changes in blood lactate levels.
Key Words: lactic acid; lactate; sweat; exercise
The search for noninvasive methods for analysis of physiologically signicant substances attracts great attention in recent years. Along with high availability, these methods should be sufciently sensitive and selective [2].
Lactate (the nal product of tissue glucose metabolism) is present in the blood, saliva, urine, and skin excretion and is one of the substances most important for analysis. The data on blood lactate concentration are essential for monitoring oxygen decit in clinical medicine and sports physiology [1,3].
Measurement of venous blood lactate is an important diagnostic test for evaluation of shock and hypoxia. Lactate level and the time course of its changes are prognostic criteria for predicting the development of lesions in sepsis, trauma, shock, and burns. In sports physiology, lactate level reects exercise intolerance in the athletes [8,12].
Two approaches to measurements of blood lac-tate concentrations are used at present in clinical and sports practice: electrochemical and spectrophotomet-
ric. However, analysis of venous and capillary blood, obligatory in both cases, is difcult and has to be performed by highly qualied medical staff with consideration for rigid hygienic regulations [1-3].
The procedure can be simplied by using easily available biological uids, e.g., sweat. Together with water, the sudoriferous glands release many metabolites: urea, some salts, uric acid, and lactate.
We...