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Amyloidosis is an extracellular deposition of abnormal serum proteins. Systemic amyloidosis could involve different organs such as the spleen, liver, and kidneys. Renal artery microaneurysm is very rare in renal amyloidosis. We report a 44-year-old woman who was referred to our general hospital for evaluation of rising serum creatinine level, anemia, and pathological fracture. Two hours following renal biopsy, she developed severe pain in the left flank during voiding and ultrasonography revealed a large perinephric hematoma. She underwent angiography that incidentally showed pseudoaneurysm with diffused renal artery microaneurysm. The feeding artery to the pseudoaneurysm was completely ligated by an interventional radiologist. The subsequent histopathological report of the kidney revealed amyloidosis.
IJKD 2016;10:94-6
www.ijkd.org
Keywords. amyloidosis, microaneurysm, renal artery, multiple Myeloma, hematoma
INTRODUCTION
Amyloidosis is an uncommon disease characterized by an extracellular deposition of abnormal serum proteins. This may involve different organs and may cause progressive organ dysfunction. Renal involvement, pericardial and pleural effusions, cardiomyopathy, and cholestatic liver disease are some of the manifestations of systemic amyloidosis.1,2 Renal involvement may cause acute kidney injury with proteinuria of nephrotic syndrome or kidney failure.3 Spontaneous rupture of organs is another complication. Rupture of the spleen and liver was reported in some cases secondary to systemic amyloidosis.4 On the other hand, increased risk of bleeding due to renal artery microaneurysm has been linked to some of the diseases which involved the kidney. Renal artery microaneurysm has been presented in some cases of systemic lupus erythematosus and polyarteritis nodosa.5-7 To our knowledge, this is the first report of renal artery microaneurysm with systemic amyloidosis.
CASE REPORT
The patient was a 44-year-old woman with a history of pathological fracture of the neck of left femur who...