Content area

Abstract

The measurement of specific salivary enzyme activity may be valuable in the diagnosis of human periodontal disease. Alkaline phosphatase has often been measured as possible indicators of gingival inflammation and bone metabolism. It has been found that untreated adult periodontitis patients exhibited higher level of alkaline phosphatase in whole saliva than did healthy control. Alkaline phosphatase levels change in relation to gingival inflammation and bone loss. 30subjects (each having at least 20 teeth) in the age18-55 years (10 subjects with healthy periodontium, 10 with generalized gingivitis and 10 with generalized periodontitis) were randomly selected. Unstimulated whole saliva collected from each subject was transferred to auto analyzer to measure the salivary alkaline phosphatase levels. The quantitative analysis of salivary alkaline phosphatase levels of samples obtained from subjects with healthy periodontium, generalized gingivitis, generalized periodontitis showed, 18.50±5.07 IU, 39.49± 9.97IUand 85.18±16.85IU (mean± standard deviation), respectively. The present results showed the potential value of salivary alkaline phosphatase level as indicator for periodontal disease status. [PUBLICATION ABSTRACT]

Details

Title
Salivary Alkaline Phosphatase level as Diagnostic marker for periodontal disease
Author
Kumar, Randhir; Sharma, Geeta
Pages
81-85
Section
Periodontology: Short Communication
Publication year
2011
Publication date
Oct 2011
Publisher
Medknow Publications & Media Pvt. Ltd.
ISSN
09767428
e-ISSN
09761799
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
912731529
Copyright
Copyright International Society of Preventive & Community Dentistry Oct 2011