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Japan - Sarpogrelate was approved in July 1993 (Anplag) and March 1999 and is indicated as a platelet aggregation inhibitor to improve peripheral circulation in the treatment of ischaemic symptoms observed in chronic arterial obstruction.
At the time of its approval, gastrointestinal haemorrhage associated with the use of sarpogrelate was included in the section on other adverse reactions. In May 1996, haematemesis, epistaxis and...
