Content area
Full Text
Nobel prize winning pharmacologist who discovered how aspirin works
John Vane's contribution to society was the science underpinning the finding that a daily low dose of aspirin prevents heart attacks and strokes, saving millions of lives each year, and the development of angiotensin converting enzyme (ACE) inhibitors for the treatment of hypertension. He made huge advances to our knowledge of inflammation and in 1982 he won a Nobel prize for medicine or physiology for discovering how aspirin works-sharing it with Sune Bergström and Bengt Samuelsson of Sweden.
He was awarded a Lasker prize (often a precursor to a Nobel) in 1977, which he also shared with Bergström and Samuelsson. In 1984 the British government recognised his outstanding achievements and gave him a knighthood in the New Year honours.
John Vane was born in Tardebigg, Worcestershire. As a boy he blew up the kitchen with a chemistry set, so his father built a shed in the garden in which he could do his experiments. He read chemistry at Birmingham University, graduating at 19, before taking a degree in pharmacology at Oxford. He graduated in 1949 and went on to a DPhil, spending a year out to lecture in pharmacology at Sheffield University. In 1953 he went to Yale University, Connecticut, for two years, and...