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ABSTRACT:
The objective is to study the effect of topical silver nano gel on wound healing. The effect of topical silver nano gel on wound healing was tested on 50 cases of surgical wounds of any origin out of which one group of 25 cases were treated with topical nano silver gel and other similar group of 25 cases were treated with conventional dressings such as betadine, hydrogen peroxide and Vaseline gauge etc. The effect of topical nano silver gel on wound healing was found to be significantly higher than conventional dressings. Nano Silver gel was found to be very good antiseptic, anti inflammatory and anti microbial as compared to conventional antiseptics in our study of 50 cases.
Key words: Nano silver gel, wound healing.
INTRODUCTION
Silver is well known as an antiseptic agent (silver nitrate and silver sulphadiazine) for ages. However, the delivery system in the form of a salt has been a limiting factor for its successful and widespread biological use. The development of nanochemistry has produced micro fine particles which increase silver's solubility and releases silver ions in concentration of 70-100 ppm. Nanocrystalline silver system kills all microbes found in the wound including fungi, MRSA and vancomycin-resistant enterococcus (VRE). In this study the effect of topical nano silver gel was studied.
MATERIALS AND METHODS
This prospective study was conducted on 50 patients from Surgical wards of Guru Nanak Dev hospital, Amritsar between 2013-2016. Wound anywhere over body due to diabetes, burn, trauma, vascular or any other pathology were included. Patients were divided into 2 groups of 25 each, in group 1 nano silver gel was applied over the wound after cleansing the wound with conventionally used materials as povidone iodine, hydrogen peroxide, Vaseline gauze etc where as in group 2 only conventional dressing was done without nano silver and it served as a control group. In both the groups dressing was done on alternate days.
Exclusion criteria:
1. Patients with total serum protein less than 5.5 mg/dl
2. Patients with Haemoglobin < 8 mg/dl.
3. Patients on immunosuppressants
4. Malignant ulcers.
5. Uncontrolled Diabetes.
6. Deep burn wounds.
7. Uraemia
8. Jaundice
9. DVT
10. Tuberculosis
FOLLOW UP-
Patients were followed up to either healing of wound...