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Abstract
A scheme for producing the α-emitters ^sup 212^Pb and ^sup 212^Bi, to be used in a promising method of diagnostics and therapy in oncology - radioimmunotherapy, is proposed. The technology is based on two generators operating in tandem: ^sup 228^Th/^sup 212^Pb and ^sup 212^Pb/^sup 212^Bi. The first one is based on separation from an initial solution containing thorium isotopes and gaseous ^sup 220^Rn, which secures the purity of the desired products ^sup 212^Pb and ^sup 212^Bi. For a ^sup 228^Th/^sup 212^Pb model generator, the efficiency of ^sup 220^Rn extraction from solution was ~60%. After conditioning, the ^sup 212^Pb solution from the ^sup 228^Th/^sup 212^Pb generator was used to charge a column, which functioned as a ^sup 212^Pb/^sup 212^Bi generator, with a cation exchanger.[PUBLICATION ABSTRACT]