Content area
Abstract
Highlights
* Vaxfectin-gD2/UL46/UL47 DNA vaccine effective against genital herpes in guinea pigs. * Prophylactic immunization prevents primary and recurrent skin disease. * Prophylactic immunization greatly reduces latent HSV-2 DNA in dorsal root ganglia. * Therapeutic immunization reduces recurrent genital disease and days of viral shedding.
Details
Title
A Vaxfectin?-adjuvanted HSV-2 plasmid DNA vaccine is effective for prophylactic and therapeutic use in the guinea pig model of genital herpes
Author
Veselenak, Ronald L; Shlapobersky, Mark; Pyles, Richard B; Wei, Qun; Sullivan, Sean M; Bourne, Nigel
Pages
7046-7051
Publication year
2012
Publication date
Nov 19, 2012
ISSN
0264410X
e-ISSN
18732518
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
1625879044
Copyright
Copyright Elsevier Limited Nov 19, 2012